What is Minerva?

Minerva is a database of clinical trials with patients with attention deficit hyperactivity disorder (ADHD) that allows for quick queries, reviews and meta-analyses as the researcher skips the study identification and extraction stages of data.

Minerva is a database containing comprehensive information on all randomized clinical trials investigating the effects of medications in patients with attention deficit hyperactivity disorder (ADHD). We have identified clinical trials investigating the efficacy and/or safety of the pharmacological treatment of ADHD using multiple information sources. We have extracted administrative information, study design, characteristics of the patients, results and the risk of bias of all clinical trials (for detailed information on Minerva see  Database design).

The information is stored in such a way that summary tables of clinical trials can be generated automatically. This information can also be easily exported for statistical analysis using common statistical analysis and meta-analysis software such as STATA, SPSS, SAS, CMA, R, Matlab, Python, Excel, or Review Managers.

Minerva in figures

Currently, Minerva contains information on over 350 randomized clinical trials (RCTs) published in almost 800 scientific articles, documents from regulatory agencies and pharmaceutical industry, and RCTs registries such as or

These clinical trials have included more than 25,000 patients. Children and adolescents represent almost 60% of the study population of these clinical trials. The presence of a psychiatric comorbidity is an inclusion criterion in 20% of the studies. Stimulants (methylphenidate and amphetamine derivatives) are the most frequently investigated medications.

How does Minerva Database help its users?


Save time and money as the use of Minerva database allows to skip study identification and data extraction.


The database contains comprehensive information on the design, patients, interventions, and results of each clinical trial.

Validity of information

The information available in Minerva Database has been used in numerous published studies.

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